Associate Scientist Assay Development EnVivo Pharmaceuticals
We seek a team-oriented and motivated individual who will be a key contributor to the overall success of the Research Department. The Associate Scientist will provide scientific excellence and guidance in ongoing projects in the In vitro Biology Group. He/she will play a primary role in development and execution of key assays for target identification and validation.
Provide expertise in the design of cellular and cell-free assays to support target identification and validation.
Perform cellular and biochemical assays to support the advancement of existing programs and identification of new targets.
Assist in the design and execution of medium/high-throughput screens to identify and validate compounds that modulate activity of new drug targets.
Assess and identify appropriate vendors/CROs for outsourcing of key activities
Monitor the scientific literature and identify and implement new technologies that drive advancement of programs
Represent the In Vitro Biology team at Project Team Meetings and external meetings, demonstrating excellent presentation skills
Assist in the identification and validation of new drug targets for neurodegenerative disease.
Master?s degree in Cell Biology, Biochemistry, or related discipline and at least 5 years of experience in the Biotech/Pharmaceutical industry.
Experience designing and executing cell-based, biochemical, and imaging assays
Experience with metabolic labeling techniques and hands-on experience working with radioisotopes
Experience with cell biological and biochemical techniques (Microscopy, Western Blotting, Immunoprecipitation, ELISA, RT-PCR, si/shRNA knockdown, lentiviral overexpression)
Experience with medium-high throughput screening assays and associated data handling/analysis
Background in neurodegenerative disease research research (Alzheimer?s Disease, Parkinson?s Disease, ALS, FTD)
Experience with primary neuronal/microglial cultures
Experience with robotics and automation of sample handling
Experience with human iPS cells a plus
||480 Arsenal Street |
Watertown, MA 02472