Watertown Categories:
Principal Scientist, Medicinal Chemistry EnVivo Pharmaceuticals
Job Summary:This position is to be an integral member of the medicinal chemistry team with project leadership responsibilities guiding external medicinal chemistry activities toward the discovery of novel CNS therapeutic agents. The position will report to the Director of Chemistry.
Key responsibilities include:
Manage all aspects of a CNS medicinal chemistry discovery program, including novel target design and synthesis, SAR development and project leadership, from conception through recommendation
Contribute to additional discovery programs as an active team member
Communicate chemistry and project results at departmental meetings
Contribute to the preparation of patent filings
Provide intellectual leadership to program direction and departmental priorities
Guide external chemistry resources through effective communication of science and program priorities
Maintain EnVivo?s leadership role in CNS research by staying abreast of current scientific thought, trends, and opportunities through active pursuit of the literature, attendance at scientific meetings and engagement with the scientific community
Interpret DMPK and biological data to advance new hypotheses and directions for iterative drug design
Apply modern computational tools to help advance programs
Maintenance of SAR tables and generation of data plots
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Candidate:
The successful candidate will be able to lead a medicinal chemistry program to the identification of novel compounds with high efficacy and safety for the treatment of CNS disorders.
Requirements:
Ph.D. in synthetic organic or medicinal chemistry with 7-15 years of relevant postdoctoral or industry experience
Candidate will have demonstrated a high level of success in one or more drug discovery programs, preferably in the CNS area
Experience with data mining programs such as Spotfire or Dotmatics
Expert knowledge of medicinal chemistry and scientific principles
Track record of significant scientific publications and patents
Strong collaborative skills in interdisciplinary settings
Desire to work in a small, team oriented, success driven environment where impact and influence of the individual are both maximized and valued
| Location: | 480 Arsenal Street Building 1 Watertown, MA 02472 United States |
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EnVivo Pharmaceuticals
Investors: BCM Technologies, Fidelity BiosciencesAll Jobs: at EnVivo Pharmaceuticals
| Web Site: | www.envivopharma.com |
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| Headquarters: | 480 Arsenal Street Building 1 Watertown, MA 02472 United States |
| Industry: | Biotechnology |
