Research Associate Syros Pharmaceuticals
THIS JOB HAS EXPIRED Syros Pharmaceuticals is an innovative drug discovery company focused on discovering and developing first-in-class medicines targeting gene control for the treatment of cancer and related conditions. Syros was founded in 2012 by leading scientists from the Whitehead Institute and the Dana Farber Cancer Institute and is supported by top venture firms and a world class Scientific Advisory Board. Combining new insights into enhancer function with information from genome wide profiling, new targets and new chemical approaches, Syros is unlocking the process of gene control for drug discovery.
Syros Pharmaceuticals is seeking an experienced research associate to join a team of highly motivated scientists that are using recent fundamental insights into transcriptional regulation to discover novel small molecules for the treatment of cancer.
The candidate must have 3-5 years of experience in academia or industry designing and running biochemical assays in high and low throughput formats.
--Design and execution of biochemical assays for multiple protein targets
--Performance of medium to high throughput screening assays
--Confirmation and potency determination of individual hits
--Investigation of molecular mechanism of selected small molecules
--Performance of cellular assays for further compound characterization
--Integrated data analysis and interpretation
--BS or MS degree in Biochemistry or related field with 3-5 years of experience in academia or industry
--Knowledge of state of the art kinase assay technologies and equipment
--Basic understanding of kinetics and thermodynamics and how it applies to the design of small molecule biochemical assays
--Experience with mammalian cell culture including expression and shRNA vectors
--Experience with multiple protein classes
--Strong attention to detail and the ability to handle multiple tasks
--Desire and ability to work in a fast paced, cross-functional and flexible team environment
--Strong interpersonal skills
--Strong verbal and written communications skills
Candidates who are keen experimentalists, enthusiastic team players that have a passion for drug discovery are encouraged to apply. Knowledge of cancer biology and transcriptional regulation is a plus.
THIS JOB HAS EXPIRED