Senior Director/Director of StatisticsCrescendo Bioscience
Job Description: Overall responsibility for statistical aspects of clinical study design, algorithm
development, health economics assessment, data mining, quality control and product development.
Manage statistics group and external consultants. Decision maker on statistical evaluation of clinical
trials protocols and will play a key role in this area in interactions with regulatory agencies. Involved in
the development of new in silico methods of biomarker discovery for molecular diagnostics. Key
interactions with bioinformatics/software development, clinical laboratory, research, process
development/automation and clinical groups.
Requirements: The successful candidate will have a PhD in statistics, bioinformatics, biochemistry,
biophysics, or a related field and at least 10 years' experience working in pharmaceutical, molecular
diagnostics, or biomedical research. Experience in working in and/or leading multidisciplinary teams,
composed of molecular biologists/bioinformaticians, process development and automation scientists,
clinicians, and software developers is key as are excellent communication skills. Interest in underlying
biology a plus. Experience with the analysis of large datasets is required; the ability to program in a
variety of computer languages (R, SAS, others) is a plus. Experience with product development and
research in auto-immune diseases preferred.
? Analysis of clinical trial data
? Lead statistical model development for products
? Report to senior management on statistical and model development issues
? Responsible for department budget and goals
? Responsible for working with the clinical laboratory and process development/automation
groups to development appropriate QC metrics
? Responsible for the statistical support for commercial laboratory
? Responsible for working with the clinical group on clinical study design
? Responsible for working with research group in design of discovery experiments and evaluation
of new technologies.