Senior Scientist, Targeting Chemistry BIND Therapeutics
THIS JOB HAS EXPIRED BIND Therapeutics is seeking an innovative, experienced and highly motivated Senior Scientist to play a key role in our Targeting Chemistry group. The successful candidate will bring their experience in the design, synthesis and conjugation of small molecules and peptides to help lead BIND in the development of highly novel targeted nanotherapeutics. They will be action-oriented and will possess excellent collaboration and communications skills, and will thrive in an interactive, dynamic team-oriented culture.
Provide strong technical and strategic input to our scientific development.
Synthesize, purify and characterize novel small molecules and peptides.
Design and synthesize analogs and optimize binding affinities for newly discovered ligands and conjugate them to nanoparticles.
Collaborate with polymer chemists to determine scalable synthetic routes for polymer-ligand conjugates.
Interface with biology/assay group to establish and execute binding assays for new ligands.
Effectively work in a cross-functional environment with Analytical Development, Pharmaceutical Science, Biology and Process Development groups.
Organize, evaluate, and present data in an effective and scientific manner.
Ph.D. In organic or bio-organic chemistry or closely related field or equivalent experience and 5-10 years of industry experience.
Hands on experience in the design and synthesis of small molecules and/or peptides using state of the art methods and instrumentation.
Experience with HPLC, LC/MS and NMR and other common analytical techniques is required.
Experience in bio-conjugation and relevant biochemical methods is a plus (biotinylation, fluorescence, SEC, FPLC, SDS-PAGE).
Experience in protein binding methods is desirable (SPR-Biacore, calorimetry, ELISA, FACS).
Experience in polymer chemistry is valued but not necessary.
Outstanding interpersonal and communications skills, with a history of collaborative cross-functional interaction.
||325 Vassar Street |
Cambridge, MA 02139
THIS JOB HAS EXPIRED